Then in 2013, GlaxoSmithKline shut down Sirtris Pharmaceuticals completely, but indicated that they would be following up on many of Sirtris’s other sirtuins-activating compounds (Click here to read more on this). Explore. The report includes information on current developmental pipeline, complete with latest updates, and features on discontinued and dormant projects. Their focus to date has been on the development of SIRT1 activators for the treatment of Type 2 Diabetes Mellitus (T2DM). ", "Doubts Build On Glaxo's Antiaging Drugs", "Sirtuins: Antiaging Medicines or Marketing? The Pharmaceutical Industry And Health Professional Services. Pharmaceutical Preparations . [5][17][18] At that time, GSK/Sirtris' lead candidate was SRT2104, described as a "first-generation sirtuin-activating compound. Sirtris Pharmaceuticals is funded by 10 investors. WhatsApp acquired by Facebook). Consultant to the CEO Jan 2004 to Jan 2006 Kevin Bitterman. Pathway-oriented platforms are rare, and dealmaking around them can be complicated: partner too early or for too little and you risk giving away the store. Sirtris Pharmaceuticals Inc. has been sold for $720 million to international pharmaceutical company GlaxoSmithKline (NYSE: GSK), just four years after the biotechnology startup launched. CLAIM THIS BUSINESS. The firm is mulling to relocate some of the 60 staffers currently working at the site in Cambridge to Philadelphia office. As followers of the drug industry know, GlaxoSmithKline famously paid $720 million to buy Sirtris Pharmaceuticals in 2008. Thomas Salzmann is Former Chairman at Satori Pharmaceuticals Inc. See Thomas Salzmann's compensation, career history, education, & memberships. Sirtris Pharmaceuticals has established a drug discovery capability to exploit sirtuin modulation for the treatment of human disease, an approach that has the potential to generate multiple clinically and commercially important products. PA. Collegeville. [1], The company was specifically focused on resveratrol formulations and derivatives as activators of the SIRT1 enzyme; Sinclair became known for making statements about resveratrol like: “(It's) as close to a miraculous molecule as you can find.... One hundred years from now, people will maybe be taking these molecules on a daily basis to prevent heart disease, stroke, and cancer.”[1] Most of the anti-aging field was more cautious, especially with regard to what else resveratrol might do in the body and its lack of bioavailability. Find 424 listings related to Sirtris Pharmaceuticals Inc in Cambridge on YP.com. Their stock opened with $10.00 in its May 23, 2007 IPO. [15][16], In 2013 GSK shut down Sirtris and its development candidates were absorbed into GSK, where research and development continued. Sirtris is the most high-profile shop working on sirtuins and resveratrol-like pharmacology, which subject has received a massive amount of … New Pathway for Developing Treatments for Diseases of Aging. Founded in 2004, Sirtris went public in May 2007 and continues as an independent discovery performance unit within GSK. Sirtris Pharmaceuticals: Living Healthier, Longer Fortune, February 12, 2007. Whether any of those compounds are going to be tested on Parkinson’s disease is yet to be determined. Type 2 Diabetes (T2D) has reached epidemic proportions in the United States. [15][16] The company said at that time that it was focused on two compounds called SRT2104 and SRT2379 that were not resveratrol analogs, had better drug-like qualities, and were more selective SIRT1 activators. The research is at a very early stage and it may take years before the drug could be submitted for approval. Sirtris Pharmaceuticals, Inc. was founded in 2008. Many people from all over the world come to the United Stats to turn their Wheel of Fortune. GlaxoSmithKline (GSK) has offered to buy all outstanding shares of Sirtris Pharmaceuticals for $22.50 a share. Xconomy Boston — [Updated 2:25 pm ET, 3/13/13] GlaxoSmithKline is closing down Cambridge, MA-based Sirtris Pharmaceuticals, almost five … Professor Toby Stuart and Senior Researcher the FDA require that animals of both sexes be included in non-clinical studies? Their focus to date has been on the development of SIRT1 activators for the treatment of Type 2 Diabetes Mellitus (T2DM). The field of sirtuins received high profile exposure last year when GlaxoSmithKline paid $720m to acquire Sirtris Pharmaceuticals, one of the few companies developing a clinical stage pipeline of products which interact with these enzymes which regulate multiple metabolic pathways. Sirtris Pharmaceuticals has raised a total of $82M in funding over 4 rounds. Global Market Direct's pharmaceuticals report, "Sirtris Pharmaceuticals, Inc. - Product Pipeline Review - 2013" provides data on the Sirtris Pharmaceuticals, Inc.'s research and development focus. See reviews, photos, directions, phone numbers and more for Sirtris Pharmaceuticals Inc locations in Cambridge, MA. Health Centers; Information by Medical Specialty; Homepages; Health Websites; Buy Online Sirtris Pharmaceuticals acquired by GlaxoSmithKline, Name of the organization that made the acquisition, Total amount raised across all funding rounds, Total number of current team members an organization has on Crunchbase, Total number of investment firms and individual investors, Descriptive keyword for an Organization (e.g. Sirtris Pharmaceuticals is a biopharmaceutical company developing and commercializing novel therapeutics that modulate sirtuins, a recently discovered family of enzymes that promotes the body's natural defense against disease. See reviews, photos, directions, phone numbers and more for Sirtris Pharmaceuticals Inc locations in Cambridge, MA. For the biopharma industry investment, business development and competitive intelligence professionals who require information to support financing, partnering and licensing activities, BCIQ provides accurate information and context to support profitable and strategic decision making. Get information, directions, products, services, phone numbers, and reviews on Sirtris Pharmaceuticals in Collegeville, undefined Discover more Pharmaceutical Preparations companies in Collegeville on … Seed, Series A, Private Equity), Whether an Organization is for profit or non-profit, General contact email for the organization, Auto-generated name of transaction (e.g. As followers of the drug industry know, GlaxoSmithKline famously paid $720 million to buy Sirtris Pharmaceuticals in 2008. Sirtris has generated a lot of hype because it is developing anti-aging drugs, some of which are based on resveratrol, a chemical in red wine. Eric W Jacobson is Chief Medical Officer at Sirtris Pharmaceuticals Inc. See Eric W Jacobson's compensation, career history, education, & memberships. Dear David: Thank you for agreeing to become a consultant to Sirtris Pharmaceuticals, Inc. (the "Company"). Solved Sirtris Pharmaceuticals: Living Healthier, Longer (Abridged) case study solution include SWOT Analysis, PESTEL Analysis, VRIO Analysis, Porter Five Forces Analysis & Value Chain Analysis, BCG Growth Share Analysis. By continuing to ... Use your energy where it's needed most — ensuring that your products are in compliance and … Sirtris is the most high-profile shop working on sirtuins and resveratrol-like pharmacology, which subject has received a massive amount of … Really? ", "SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1", "Doubt on Anti-Aging Molecule as Resveratrol Trial Is Halted", "GlaxoSmithKline Halts All Further Development Of Resveratrol Drug SRT501", "GSK absorbs controversial 'longevity' company : News blog", "GlaxoSmithKline Shuts Down Sirtris, Five Years After $720M Buyout", https://en.wikipedia.org/w/index.php?title=Sirtris_Pharmaceuticals&oldid=968238491, Biotechnology companies of the United States, Creative Commons Attribution-ShareAlike License, This page was last edited on 18 July 2020, at 03:23. The deal is another example of Pharma's interest in platform biotechs and its hunger for innovation. The buyout was another giant coup for Sirtris … Medvedik has worked as a biotechnology consultant at Sirtris Pharmaceuticals and has taught molecular and synthetic biology to hundreds of students while at Harvard University, The Cooper Union, School of Visual Arts, Genspace and NYU. Should the company establish a proposed alliance with a pharmaceutical firm? Stay up to date on the latest stock price, chart, news, analysis, fundamentals, trading and investment tools. 1250 S COLLEGEVILLE RD COLLEGEVILLE, PA 19426 Get Directions (585) 275-5774. Business Info. Living in the United States has Advantages over living in my country America- A country of Immigrants. Sirtris Pharmaceuticals is registered under the ticker NASDAQ:SIRT . GlaxoSmithKline (GSK) is closing its Sirtris Pharmaceuticals office in Cambridge and fully integrating its research and development (R&D) operations with Philadelphia office. Sirtris Pharmaceuticals Presents Results of Studies of SIRT1 Activators at 6th Annual Metabolic Diseases Drug Discovery and Development World Summit, July 17, 2007 CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jul 17, 2007 - Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging, … Just what did GlaxoSmithKline (GSK) get for its dime when, in 2008, it dropped $720 million (or 72 billion dimes) to buy Sirtris Pharmaceuticals? In most courses studied at Harvard Business schools, students are provided with a case study. GlaxoSmithKline (NYSE: GSK) has announced that it has entered into a definitive acquisition pact with Sirtris Pharmaceuticals Inc. (NASDAQ: SIRT). Private Company Reports provide up to date insight into the structure and operations of privately-held pharmaceutical, biotechnology and biomedical companies.S… GlaxoSmithKline plc (NYSE: GSK) announced today the successful completion of the tender offer by its wholly-owned subsidiary Fountain Acquisition Corporation (FAC) for shares of common Sirtris Pharmaceuticals Inc., a biopharmaceutical company engaged in developing small molecule drugs that target the sirtuins, a recently discovered family of seven enzymes associated with the aging process, was acquired by GlaxoSmithKline (NYSE: GSK) in June of 2008 and now operates as the company’s wholly-owned subsidiary. 481 - 490 of 500 . Dr. David Sinclair is co-founder of several biotechnology companies (Sirtris Pharmaceuticals, Genocea Biosciences, OvaScience, CohBar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others (most notably Shaklee). Should the company establish a proposed alliance with a pharmaceutical firm? See Appendix for pictures of the covers of the Wall Street Journal and Fortune. Rare, Progressive Disorder Caused by Mutation in DNA of Mitochondria Has No Known Treatments CAMBRIDGE, MA, USA | August 9, 2007 | Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging such as Type 2 Diabetes, today announced the initiation of a Phase 1b clinical trial … Should it create a nutraceuticals business in parallel to its effort to develop anti-aging therapeutics? Product Status Description; There are no products. GSK is one of the largest pharmaceutical companies in the world, headquartered in London; it has significant products in both consumer and pharmaceutical areas. We use cookies to provide you with a better experience. Sirtris Pharmaceuticals From Wikipedia, the free encyclopedia Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Sirtris Pharmaceuticals, Inc. specializes in Pharmaceutical Preparations. Describes a set of key strategic decisions facing the scientific founder and CEO of a promising, early stage bio-pharmaceuticals company. N9-808-112 MARCH 18, 2008 TOBY STUART DAVID KIRON Sirtris Pharmaceuticals: Living Healthier, Longer “You can live to be a hundred if you give up all the things that make you want to live to be a hundred. The successful organizations such as Sirtris Gsk's are the one who able to predict market trends better than others, provide resources to develop products and services to leverage those trends, able to counter competitors’ threats, and meet customers’ expected value proposition. Sirtris Pharmaceuticals, Inc. S. Sirtris Pharmaceuticals, Inc. GlaxoSmithKline acquires Sirtris Pharmaceuticals for approximately $720 million through a cash tender offer and merger of $22.50 per share, the firms state June 6. Sirtris Pharmaceuticals Inc Sirtris Pharmaceuticals, Inc. operates as a biopharmaceutical company. Sirtris Pharmaceuticals Team Add Team Member. Sirtris Pharmaceuticals has established a drug discovery capability to exploit sirtuin modulation for the treatment of human disease, an approach that has the potential to generate multiple clinically and commercially important products. London-based Glaxo said Tuesday it agreed to buy Sirtris in an all-cash tender offer at $22.50 a share. Person Role Period; Brian Shin. And that was the case when GlaxoSmithKline, the British drug company with U.S. headquarters in the Triangle, announced its $720 million purchase of Massachusetts’ Sirtris Pharmaceuticals. In 2008, GlaxoSmithKline (GSK) purchased Sirtris Pharmaceuticals for $720 million in order to continue to expand its portfolio of potential drugs to be commercialized in the future. GlaxoSmithKline (GSK) to Acquire Sirtris Pharmaceuticals, a World Leader in "Sirtuin" Research and Development for $720M 4/23/2008 LONDON, PHILADELPHIA AND CAMBRIDGE, Mass., April 22 -- Their focus to date has been on the development of SIRT1 activators for the treatment of Type 2 Diabetes Mellitus (T2DM). Sirtris Pharmaceuticals has established a drug discovery capability to exploit sirtuin modulation for the treatment of human disease, an approach that has the potential to generate multiple clinically and commercially important products. Should the company establish a proposed alliance with a pharmaceutical firm? Professor Toby Stuart and Senior Researcher Advantages of Living in America. And Sirtris/GSK faces long years of rigorous research before this nook of the anti-aging field yields a marketed drug. CAMBRIDGE, Mass.- Sirtris Pharmaceuticals, Inc. , a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging, announced today publication of a study by Sirtris and Harvard University scientists … San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. But Sirtris pulled it off, via M&A, when GSK tendered a whopping $720 million for it in April. Sirtris Pharmaceuticals: Living Healthier, Longer by Toby Stuart , David Kiron , (No reviews yet) Write a Review Sirtris Pharmaceuticals, Inc. – Mergers & Acquisitions (M&A), Partnerships & Alliances and Investment Report Project Synopsis: MarketLine's Company Mergers & Acquisitions (M&A), Partnerships & Alliances and Investments reports offer a comprehensive breakdown of the organic and inorganic growth activity undertaken by an organization to sustain its competitive advantage. Pharmaceutical Preparations. Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. 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